OR6T1

Protein-coding gene in the species Homo sapiens
OR6T1
Identifiers
AliasesOR6T1, OR11-277, olfactory receptor family 6 subfamily T member 1
External IDsGeneCards: OR6T1; OMA:OR6T1 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR6T1
Genomic location for OR6T1
Band11q24.1Start123,942,867 bp[1]
End123,943,838 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • body of pancreas

  • rectum

  • mucosa of transverse colon

  • islet of Langerhans
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • signal transducer activity
  • neurotransmitter receptor activity
  • G protein-coupled serotonin receptor activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
  • integral component of plasma membrane
  • dendrite
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • signal transduction
  • response to stimulus
  • G protein-coupled serotonin receptor signaling pathway
  • G protein-coupled receptor signaling pathway
  • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
  • chemical synaptic transmission
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

219874

n/a

Ensembl

ENSG00000181499

n/a

UniProt

Q8NGN1

n/a

RefSeq (mRNA)

NM_001005187

n/a

RefSeq (protein)

NP_001005187

n/a

Location (UCSC)Chr 11: 123.94 – 123.94 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 6T1 is a protein that in humans is encoded by the OR6T1 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

  • Olfactory receptor

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181499 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR6T1 olfactory receptor, family 6, subfamily T, member 1".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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