OR4M2

Protein-coding gene in the species Homo sapiens
OR4M2
Identifiers
AliasesOR4M2, OR15-3, olfactory receptor family 4 subfamily M member 2
External IDsGeneCards: OR4M2; OMA:OR4M2 - orthologs
Gene location (Human)
Chromosome 15 (human)
Chr.Chromosome 15 (human)[1]
Chromosome 15 (human)
Genomic location for OR4M2
Genomic location for OR4M2
Band15q11.2Start22,070,241 bp[1]
End22,083,221 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • gonad

  • left testis

  • right testis

  • human musculoskeletal system

  • skeletal striated muscle

  • muscle of leg

  • gastrocnemius muscle
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • olfactory receptor activity
  • transmembrane signaling receptor activity
  • signal transducer activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
Biological process
  • sensory perception of smell
  • detection of chemical stimulus involved in sensory perception of smell
  • detection of chemical stimulus involved in sensory perception
  • signal transduction
  • response to stimulus
  • G protein-coupled receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

390538

n/a

Ensembl

ENSG00000274102
ENSG00000288194

n/a

UniProt

Q8NGB6

n/a

RefSeq (mRNA)

NM_001004719

n/a

RefSeq (protein)

NP_001004719

n/a

Location (UCSC)Chr 15: 22.07 – 22.08 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 4M2 is a protein that in humans is encoded by the OR4M2 gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

See also

  • Olfactory receptor

References

  1. ^ a b c ENSG00000288194 GRCh38: Ensembl release 89: ENSG00000274102, ENSG00000288194 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ a b "Entrez Gene: OR4M2 olfactory receptor, family 4, subfamily M, member 2".

Further reading

  • Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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Class I
(fish-like receptors)
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Class II
(tetrapod specific receptors)
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