CDKN2A

• NF-kappaB binding
• GO:0001948, GO:0016582 protein binding
• cyclin-dependent protein serine/threonine kinase inhibitor activity
• protein kinase binding
• RNA binding
• DNA binding
• p53 binding
• transcription factor binding
• MDM2/MDM4 family protein binding
• ubiquitin-protein transferase inhibitor activity
• SUMO transferase activity
• disordered domain specific binding
• GO:0090645, GO:0061637 ubiquitin ligase inhibitor activity

• цитоплазма
• гіалоплазма
• senescence-associated heterochromatin focus
• клітинне ядро
• ядерні тільця
• нуклеоплазма
• ядерце
• мітохондрія
• GO:0009327 protein-containing complex

• positive regulation of smooth muscle cell apoptotic process
• negative regulation of cyclin-dependent protein serine/threonine kinase activity
• replicative senescence
• G1 phase
• negative regulation of cell-matrix adhesion
• клітинне старіння
• negative regulation of cell growth
• positive regulation of cellular senescence
• positive regulation of macrophage apoptotic process
• клітинний цикл
• Ras protein signal transduction
• negative regulation of phosphorylation
• GO:0045996 negative regulation of transcription, DNA-templated
• negative regulation of NF-kappaB transcription factor activity
• negative regulation of cell population proliferation
• G1/S transition of mitotic cell cycle
• GO:1990376 negative regulation of G1/S transition of mitotic cell cycle
• GO:0097285 апоптоз
• regulation of G2/M transition of mitotic cell cycle
• GO:0009373 regulation of transcription, DNA-templated
• regulation of protein stability
• negative regulation of immature T cell proliferation in thymus
• regulation of protein export from nucleus
• negative regulation of protein kinase activity
• negative regulation of proteolysis involved in cellular protein catabolic process
• protein K63-linked ubiquitination
• positive regulation of signal transduction by p53 class mediator
• somatic stem cell division
• protein stabilization
• protein polyubiquitination
• positive regulation of protein sumoylation
• transcription, DNA-templated
• GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated
• autophagy of mitochondrion
• apoptotic mitochondrial changes
• regulation of protein targeting to mitochondrion
• protein destabilization
• negative regulation of ubiquitin-protein transferase activity
• positive regulation of apoptotic process
• rRNA processing
• negative regulation of ubiquitin-dependent protein catabolic process
• mitochondrial depolarization
• positive regulation of DNA damage response, signal transduction by p53 class mediator
• negative regulation of B cell proliferation
• activation of cysteine-type endopeptidase activity involved in apoptotic process
• regulation of apoptotic DNA fragmentation
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• positive regulation of protein localization to nucleus
• protein sumoylation
• GO:1901313 positive regulation of gene expression
• GO:0060564, GO:1904190 negative regulation of ubiquitin protein ligase activity
• amyloid fibril formation
• negative regulation of protein neddylation