Transmembrane and tetratricopeptide repeat containing 1

Protein-coding gene in the species Homo sapiens
TMTC1
Identifiers
AliasesTMTC1, OLF, TMTC1A, ARG99, transmembrane and tetratricopeptide repeat containing 1, transmembrane O-mannosyltransferase targeting cadherins 1
External IDsOMIM: 615855; MGI: 3039590; HomoloGene: 65299; GeneCards: TMTC1; OMA:TMTC1 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for TMTC1
Genomic location for TMTC1
Band12p11.22Start29,500,840 bp[1]
End29,784,759 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for TMTC1
Genomic location for TMTC1
Band6|6 G3Start148,133,928 bp[2]
End148,345,887 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • spinal ganglia

  • lateral nuclear group of thalamus

  • trigeminal ganglion

  • endothelial cell

  • external globus pallidus

  • pericardium

  • myocardium of left ventricle

  • deltoid muscle

  • lactiferous duct

  • synovial membrane
Top expressed in
  • secondary oocyte

  • zygote

  • interventricular septum

  • aortic valve

  • triceps brachii muscle

  • ascending aorta

  • sternocleidomastoid muscle

  • temporal muscle

  • vastus lateralis muscle

  • primary oocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • mannosyltransferase activity
  • dolichyl-phosphate-mannose-protein mannosyltransferase activity
  • transferase activity
Cellular component
  • membrane
  • integral component of membrane
  • endoplasmic reticulum
Biological process
  • RNA processing
  • protein O-linked mannosylation
  • protein glycosylation
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

83857

387314

Ensembl

ENSG00000133687

ENSMUSG00000030306

UniProt

Q8IUR5

Q3UV71

RefSeq (mRNA)

NM_001193451
NM_175861
NM_001367875
NM_031920

NM_198967
NM_001347518

RefSeq (protein)

NP_001180380
NP_787057
NP_001354804

NP_001334447
NP_945318

Location (UCSC)Chr 12: 29.5 – 29.78 MbChr 6: 148.13 – 148.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane and tetratricopeptide repeat containing 1 is a protein that in humans is encoded by the TMTC1 gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000133687 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030306 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Transmembrane and tetratricopeptide repeat containing 1". Retrieved 2016-03-21.

Further reading


  • v
  • t
  • e