Protein asunder homolog

Protein-coding gene in the species Homo sapiens
INTS13
Identifiers
AliasesINTS13, C12orf11, GCT1, Mat89Bb, NET48, SPATA30, ASUN, asunder, spermatogenesis regulator, integrator complex subunit 13
External IDsOMIM: 615079; MGI: 1918427; HomoloGene: 10043; GeneCards: INTS13; OMA:INTS13 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for INTS13
Genomic location for INTS13
Band12p11.23Start26,905,181 bp[1]
End26,938,326 bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for INTS13
Genomic location for INTS13
Band6|6 G3Start146,549,632 bp[2]
End146,577,835 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • secondary oocyte

  • C1 segment

  • epithelium of nasopharynx

  • tibia

  • biceps brachii

  • germinal epithelium

  • Skeletal muscle tissue of biceps brachii

  • gingival epithelium

  • gonad

  • retinal pigment epithelium
Top expressed in
  • otic placode

  • saccule

  • otic vesicle

  • neural layer of retina

  • tail of embryo

  • genital tubercle

  • spermatocyte

  • epiblast

  • thymus

  • ventricular zone
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • protein binding
Cellular component
  • cytoplasm
  • nucleoplasm
  • nucleus
Biological process
  • centrosome localization
  • regulation of fertilization
  • flagellated sperm motility
  • mitotic spindle organization
  • cell cycle
  • protein localization to nuclear envelope
  • regulation of mitotic cell cycle
  • cell division
  • snRNA transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55726

71177

Ensembl

ENSG00000064102

ENSMUSG00000040250

UniProt

Q9NVM9

Q8QZV7

RefSeq (mRNA)

NM_018164

NM_138757

RefSeq (protein)

NP_060634

NP_620096
NP_001349035
NP_001349036
NP_001349037

Location (UCSC)Chr 12: 26.91 – 26.94 MbChr 6: 146.55 – 146.58 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein asunder homolog (Asun) also known as cell cycle regulator Mat89Bb homolog (Mat89Bb) is a protein that in humans is encoded by the Asun gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000064102 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040250 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Bourdon V, Naef F, Rao PH, Reuter V, Mok SC, Bosl GJ, Koul S, Murty VV, Kucherlapati RS, Chaganti RS (Nov 2002). "Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes". Cancer Res. 62 (21): 6218–23. PMID 12414650.
  6. ^ "Entrez Gene: C12orf11 chromosome 12 open reading frame 11".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Lee SY, Obata Y, Yoshida M, et al. (2003). "Immunomic analysis of human sarcoma". Proc. Natl. Acad. Sci. U.S.A. 100 (5): 2651–6. Bibcode:2003PNAS..100.2651L. doi:10.1073/pnas.0437972100. PMC 151395. PMID 12601173.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.


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