Prostaglandin E

  • G02AD (WHO)
IdentifiersCAS Number
  • 11042-70-9
ChemSpider
  • none

Prostaglandin E is a family of naturally occurring prostaglandins that are used as medications.

Types include:

  • Prostaglandin E1 also known as alprostadil
  • Prostaglandin E2 also known as dinoprostone

Both types are on the World Health Organization's List of Essential Medicines.[1]

Prostaglandin E play an important role in thermoregulation of the human brain. Decreased formation of prostaglandin E through inhibition of cyclooxygenase is the basis for the antipyretic of nonsteroidal anti-inflammatory drugs (NSAIDs).

References

  1. ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.

External links

  • "Alprostadil". Drug Information Portal. U.S. National Library of Medicine.
  • "Dinoprostone". Drug Information Portal. U.S. National Library of Medicine.
  • Prostaglandins+E at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  • v
  • t
  • e
Eicosanoids
Precursor
  • Arachidonic acid
Prostanoids
Prostaglandins (PG)
Precursor
  • H2
Active
D/J
  • D2
E/F
  • E2 (Dinoprostone)
  • E1 (Alprostadil)
  • F2α (Dinoprost):
I
  • I2 (Prostacyclin/Epoprostenol):
Thromboxanes (TX)
  • A2
  • B2
Leukotrienes (LT)
Precursor
  • Arachidonic acid 5-hydroperoxide
Initial
  • A4
  • B4
SRS-A
  • C4
  • D4
  • E4
Eoxins (EX)
Precursor
  • Arachidonic acid 15-hydroperoxide
Eoxins
  • A4
  • C4
  • D4
  • E4
Nonclassic
By function
  • labor stimulation:
    • PGE2 (Dinoprostone)
    • PGF2α (Dinoprost)
Portal:
  • icon Medicine


Stub icon

This biochemistry article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e