Protein-coding gene in the species Homo sapiens
MYL5 |
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Identifiers |
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Aliases | MYL5, myosin light chain 5, MYLC2 |
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External IDs | OMIM: 160782; HomoloGene: 48110; GeneCards: MYL5; OMA:MYL5 - orthologs |
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Gene location (Human) |
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![Chromosome 4 (human)](//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Ideogram_human_chromosome_4.svg/300px-Ideogram_human_chromosome_4.svg.png) | Chr. | Chromosome 4 (human)[1] |
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| Band | 4p16.3 | Start | 673,580 bp[1] |
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End | 682,033 bp[1] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - mucosa of transverse colon
- skin of abdomen
- right adrenal cortex
- left adrenal cortex
- left testis
- right testis
- right hemisphere of cerebellum
- skin of leg
- apex of heart
- sural nerve
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| | More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - calcium ion binding
- structural constituent of muscle
- metal ion binding
| Cellular component | - cytosol
- muscle myosin complex
- myosin complex
| Biological process | - regulation of muscle contraction
- muscle contraction
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 4: 0.67 – 0.68 Mb | n/a |
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PubMed search | [2] | n/a |
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Wikidata |
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Myosin light chain 5 is a protein that, in humans, is encoded by the MYL5 gene. [3]
Function
This gene encodes one of the myosin light chains, a component of the hexameric ATPase cellular motor protein myosin. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene product, one of the regulatory light chains, is expressed in fetal muscle and in adult retina, cerebellum, and basal ganglia.
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000215375 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Myosin light chain 5". Retrieved 2017-01-24.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.