Ergovaline
Chemical compound
- 2873-38-3 Y
- 104843
- 94635 N
- 059E2O9IV4
- DTXSID10893243
- Interactive image
- O=C3N1CCC[C@H]1[C@]2(O)O[C@](C(=O)N2[C@H]3C(C)C)(NC(=O)[C@@H]7/C=C6/c4cccc5c4c(c[nH]5)C[C@H]6N(C)C7)C
InChI
- InChI=1S/C29H35N5O5/c1-15(2)24-26(36)33-10-6-9-22(33)29(38)34(24)27(37)28(3,39-29)31-25(35)17-11-19-18-7-5-8-20-23(18)16(13-30-20)12-21(19)32(4)14-17/h5,7-8,11,13,15,17,21-22,24,30,38H,6,9-10,12,14H2,1-4H3,(H,31,35)/t17-,21-,22+,24+,28-,29+/m1/s1 N
- Key:BGHDUTQZGWOQIA-VQSKNWBGSA-N N
Ergovaline is an ergopeptine and one of the ergot alkaloids. It is usually found in endophyte-infected species of grass like Tall fescue[1] or Perennial Ryegrass.[2] It is toxic to cattle feeding on infected grass, probably because it acts as a vasoconstrictor.[1][3]
See also
- Neotyphodium coenophialum
References
- ^ a b Browning R (2003). "Tall Fescue Endophyte Toxicosis in Beef Cattle: Clinical Mode of Action and Potential Mitigation through Cattle Genetics" (PDF). Beef Improvement Federation.
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(help) - ^ Hovermale JT, Craig AM (July 2001). "Correlation of ergovaline and lolitrem B levels in endophyte-infected perennial ryegrass (Lolium perenne)". Journal of Veterinary Diagnostic Investigation. 13 (4): 323–7. doi:10.1177/104063870101300407. PMID 11478604.
- ^ Schnitzius JM, Hill NS, Thompson CS, Craig AM (May 2001). "Semiquantitative determination of ergot alkaloids in seed, straw, and digesta samples using a competitive enzyme-linked immunosorbent assay". Journal of Veterinary Diagnostic Investigation. 13 (3): 230–7. doi:10.1177/104063870101300307. PMID 11482600.
External links
- Media related to Ergovaline at Wikimedia Commons
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Ergolines
derivatives
- 2-Bromo-LSD (BOL-148)
- Amesergide
- Bromocriptine
- Cabergoline
- Dihydroergocornine
- Dihydroergocristine
- Dihydroergocryptine
- Dihydroergometrine (Dihydroergonovine, Dihydroergobasine)
- Dihydroergosine
- Dihydroergotamine
- Epicriptine
- Ergine (LSA; LA-111; Lysergamide)
- Ergocornine
- Ergocristine
- Ergocryptine
- Ergoloid (Dihydroergotoxine)
- Ergometrine (Ergonovine, Ergobasine)
- Ergometrinine
- Ergostine
- Ergotamine
- Ergotoxine
- Ergovaline
- Lisuride
- LY-215,840
- LSH
- Lysergic acid
- Lysergic acid methyl ester
- Lysergol
- Mesulergine
- Metergoline
- MIPLA
- Methysergide
- Sergolexole
lysergamides
- 1B-LSD
- 1cP-LSD
- 1P-ETH-LAD
- 1P-LSD
- AL-LAD
- ALD-52
- BU-LAD
- CYP-LAD
- Diallyllysergamide (DAL)
- Dimethyllysergamide (DAM-57)
- ECPLA
- Ergonovine
- ETFELA
- ETH-LAD
- IP-LAD
- LAMPA
- LAE-32
- LSD
- LPD-824
- LSM-775
- LSH
- LSD-Pip
- Lysergic Acid 2-Butylamide
- Lysergic Acid 2,4-Dimethylazetidide
- Lysergic Acid 3-Pentylamide
- Lysergic acid cyclobutylamide
- Lysergic acid cyclopentylamide
- Methylergometrine (Methylergonovine, Methylergobasine)
- MIPLA
- MLD-41
- PARGY-LAD
- PRO-LAD
ergolines
sources
- Achnatherum robustum (Sleepy Grass)
- Claviceps spp. (Ergot)
Morning glory: Argyreia nervosa (Hawaiian Baby Woodrose), Ipomoea spp.(Morning Glory, Tlitliltzin, Badoh Negro), Rivea corymbosa (Coaxihuitl, Ololiúqui)
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